junceus and the cytostatics: doxorubicin (DOX), cisplatin (CDPP) and paclitaxel (PTX), respectively. Materials and methods: CT26 murine colon tumor cells were treated simultaneously at a constant rate of concentrations equal to or lower than the mean inhibitory concentration (IC50) of the venom of the scorpion R. junceus scorpion venom to increase the cytotoxic effect of conventional cytostatics on colon tumor cells. Objective: To determine the potentiality of the R. However, its antineoplastic effect on murine colon tumor cells and the type of pharmacological interaction of its combination with conventional chemotherapeutic agents used in the clinic for the treatment of colon cancer have not been evaluated. junceus), decreases the viability of tumor cells of epithelial origin and has no cytotoxic effect on normal cells. Introduction: The endemic scorpion venom of Cuba, Rhopalurus junceus (R. DOI: 10.35841/2249-622X.69.4552 Visit for more related articles at Asian Journal of Biomedical and Pharmaceutical Sciences Abstract
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